Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 18/20 | 0.57 |
| ▸ | GRM5 | P41594 | 7/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23905163 | 0.88 | MAOB (0.63) | MAOBGRM5NPC1ALDH1A1HPGD | |
| SCHEMBL23906028 | 0.85 | MAOB (0.59) | MAOBGRM5NPC1ALDH1A1HPGD | |
| SCHEMBL23905927 | 0.85 | MAOB (0.72) | MAOBGRM5NPC1ALDH1A1HPGD | |
| SCHEMBL23905852 | 0.82 | MAOB (0.59) | MAOBGRM5NPC1ALDH1A1HPGD | |
| SCHEMBL23906237 | 0.82 | MAOB (0.64) | MAOBGRM5NPC1ALDH1A1HPGD | |
| SCHEMBL23882769 | 0.82 | CYP19A1 (0.43) | MAOB | |
| SCHEMBL23905963 | 0.82 | CYP19A1 (0.43) | MAOB | |
| SCHEMBL32675590 | 0.82 | CYP19A1 (0.43) | MAOB | |
| SCHEMBL23906006 | 0.82 | CYP19A1 (0.43) | MAOB | |
| SCHEMBL30251337 | 0.82 | CYP19A1 (0.43) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198283-A1 | INHIBITORS OF ANTIGEN PRESENTATION BY HLA-DR | JANSSEN PHARMACEUTICA NV (BE) | 2021-10-07 | — | — | WO | disclosed |