Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 4/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8080765 | 0.93 | FFAR4 (0.54) | FFAR4FFAR1EPHX2FAAHGPR84 | |
| SCHEMBL8081193 | 0.93 | FFAR4 (0.54) | FFAR4FFAR1EPHX2FAAHGPR84 | |
| SCHEMBL17258243 | 0.86 | USP2 (0.51) | FFAR4FFAR1EPHX2CES2MAPT | |
| SCHEMBL8536165 | 0.86 | USP2 (0.51) | FFAR4FFAR1EPHX2CES2MAPT | |
| SCHEMBL8345106 | 0.86 | USP2 (0.51) | FFAR4FFAR1EPHX2CES2MAPT | |
| SCHEMBL8079958 | 0.84 | EPHX2 (0.57) | FFAR4FFAR1EPHX2CES2CES1 | |
| SCHEMBL9576894 | 0.84 | EPHX2 (0.57) | FFAR4FFAR1EPHX2CES2CES1 | |
| SCHEMBL8080122 | 0.84 | EPHX2 (0.57) | FFAR4FFAR1EPHX2CES2CES1 | |
| SCHEMBL27530726 | 0.83 | EPHX2 (0.45) | FFAR4FFAR1EPHX2CES2FAAH | |
| SCHEMBL8066132 | 0.79 | EPHX2 (0.57) | FFAR4FFAR1EPHX2GPR84MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2538920-A1 | EMOLLIENT FOAMS FOR TREATMENT OF DERMATOSES | Precision Dermatology, Inc. (US) | 2013-01-02 | — | — | EP | disclosed |
| WO-2011106026-A1 | EMOLLIENT FOAMS FOR TREATMENT OF DERMATOSES | PRECISION DERMATOLOGY, INC. (US) | 2011-09-01 | — | — | WO | disclosed |