Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.42 |
| ▸ | GRM5 | P41594 | 6/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23905184 | 0.89 | MAOB (0.44) | MAOBGRM5NPC1ALDH1A1HPGD | |
| SCHEMBL23905994 | 0.85 | MAOB (0.38) | MAOBGRM5NPC1ALDH1A1HPGD | |
| SCHEMBL23905954 | 0.85 | MAOB (0.43) | MAOBGRM5NPC1ALDH1A1HPGD | |
| SCHEMBL23906118 | 0.85 | MAOB (0.43) | MAOBGRM5NPC1ALDH1A1HPGD | |
| SCHEMBL23905186 | 0.80 | MAOB (0.55) | MAOBGRM5NPC1ALDH1A1HPGD | |
| SCHEMBL23905188 | 0.79 | GRM5 (0.57) | MAOBGRM5NPC1ALDH1A1HPGD | |
| SCHEMBL23905175 | 0.79 | MRGPRX4 (0.47) | MAOBGRM5NPC1ALDH1A1HPGD | |
| SCHEMBL23882791 | 0.75 | CYP19A1 (0.36) | MAOBGRM5ALDH1A1SMN1; SMN2 | |
| SCHEMBL23906135 | 0.75 | CYP19A1 (0.36) | MAOBGRM5ALDH1A1SMN1; SMN2 | |
| SCHEMBL30251309 | 0.75 | CYP19A1 (0.36) | MAOBGRM5ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198283-A1 | INHIBITORS OF ANTIGEN PRESENTATION BY HLA-DR | JANSSEN PHARMACEUTICA NV (BE) | 2021-10-07 | — | — | WO | disclosed |