Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 7/20 | 0.31 |
| ▸ | LTB4R2 | Q9NPC1 | 7/20 | 0.31 |
| ▸ | HTR6 | P50406 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26159425 | 0.89 | MRGPRX4 (0.36) | MAOBGRM5MRGPRX4IDO1TDO2 | |
| SCHEMBL23905901 | 0.89 | MRGPRX4 (0.36) | MAOBGRM5MRGPRX4IDO1TDO2 | |
| SCHEMBL32675600 | 0.89 | MRGPRX4 (0.36) | MAOBGRM5MRGPRX4IDO1TDO2 | |
| SCHEMBL23882890 | 0.89 | MRGPRX4 (0.36) | MAOBGRM5MRGPRX4IDO1TDO2 | |
| SCHEMBL30251023 | 0.89 | MRGPRX4 (0.36) | MAOBGRM5MRGPRX4IDO1TDO2 | |
| SCHEMBL26160500 | 0.86 | GRM5 (0.40) | MAOBGRM5MRGPRX4LTB4RLTB4R2 | |
| SCHEMBL26160495 | 0.86 | GRM5 (0.40) | MAOBGRM5MRGPRX4LTB4RLTB4R2 | |
| SCHEMBL23882670 | 0.86 | MAOB (0.37) | MAOBGRM5MRGPRX4IDO1TDO2 | |
| SCHEMBL30251340 | 0.86 | MAOB (0.37) | MAOBGRM5MRGPRX4IDO1TDO2 | |
| SCHEMBL30250880 | 0.86 | MAOB (0.37) | MAOBGRM5MRGPRX4IDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198283-A1 | INHIBITORS OF ANTIGEN PRESENTATION BY HLA-DR | JANSSEN PHARMACEUTICA NV (BE) | 2021-10-07 | — | — | WO | disclosed |