Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30251162 | 0.90 | GRM5 (0.38) | GRM5TNFMAOBMAOAADRA1D | |
| SCHEMBL30251163 | 0.90 | GRM5 (0.38) | GRM5TNFMAOBMAOAADRA1D | |
| SCHEMBL30251244 | 0.90 | GRM5 (0.38) | GRM5TNFMAOBMAOAADRA1D | |
| SCHEMBL23882920 | 0.90 | GRM5 (0.38) | GRM5TNFMAOBMAOAADRA1D | |
| SCHEMBL26159492 | 0.90 | GRM5 (0.38) | GRM5TNFMAOBMAOAADRA1D | |
| SCHEMBL23905950 | 0.90 | GRM5 (0.38) | GRM5TNFMAOBMAOAADRA1D | |
| SCHEMBL26160495 | 0.90 | GRM5 (0.40) | GRM5TNFMAOBMAOA | |
| SCHEMBL26160500 | 0.90 | GRM5 (0.40) | GRM5TNFMAOBMAOA | |
| SCHEMBL23882746 | 0.85 | MAOB (0.36) | GRM5MAOB | |
| SCHEMBL30251349 | 0.85 | MAOB (0.36) | GRM5MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198283-A1 | INHIBITORS OF ANTIGEN PRESENTATION BY HLA-DR | JANSSEN PHARMACEUTICA NV (BE) | 2021-10-07 | — | — | WO | disclosed |