Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 9/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.48 |
| ▸ | NR0B2 | Q15466 | 2/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | RARA | P10276 | 6/20 | 0.46 |
| ▸ | RARG | P13631 | 6/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2390175 | 0.90 | RARB (0.54) | RARBPTPN11NR0B2HDAC11HDAC2 | |
| SCHEMBL2390154 | 0.87 | RARB (0.48) | RARBPTPN11NR0B2HDAC11HDAC2 | |
| SCHEMBL2392379 | 0.87 | RARB (0.51) | RARBPTPN11NR0B2HDAC11HDAC2 | |
| SCHEMBL2394296 | 0.86 | HDAC11 (0.45) | RARBHDAC11HDAC2HDAC7HDAC8 | |
| SCHEMBL2391578 | 0.86 | PTPN11 (0.53) | RARBPTPN11NR0B2HDAC11HDAC2 | |
| SCHEMBL2394189 | 0.86 | RARB (0.52) | RARBPTPN11NR0B2HDAC11HDAC2 | |
| SCHEMBL2395883 | 0.85 | PTPN11 (0.52) | RARBPTPN11NR0B2HDAC11HDAC2 | |
| SCHEMBL2391094 | 0.85 | PTPN11 (0.68) | RARBPTPN11NR0B2HDAC11HDAC2 | |
| SCHEMBL2393233 | 0.83 | RARB (0.55) | RARBPTPN11NR0B2HDAC11HDAC2 | |
| SCHEMBL6622836 | 0.83 | RARB (0.52) | RARBPTPN11NR0B2HDAC11HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE42700-E1 | Induction of apoptosis in cancer cells | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2011-09-13 | — | — | US | disclosed |