Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 13/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17457979 | 0.87 | PIK3CD (0.69) | PIK3CDKIF11 | |
| SCHEMBL17457976 | 0.87 | PIK3CD (0.69) | PIK3CDKIF11 | |
| SCHEMBL17458476 | 0.84 | PIK3CD (0.68) | PIK3CD | |
| SCHEMBL23912243 | 0.78 | PIK3CD (0.50) | PIK3CDKCNH2HRH3SMN1; SMN2ALDH1A1 | |
| SCHEMBL17458487 | 0.76 | PIK3CD (1.00) | PIK3CD | |
| SCHEMBL17458486 | 0.76 | PIK3CD (1.00) | PIK3CD | |
| SCHEMBL17458365 | 0.75 | PIK3CD (0.67) | PIK3CDKCNH2HRH3 | |
| SCHEMBL17458367 | 0.75 | PIK3CD (0.67) | PIK3CDKCNH2HRH3 | |
| SCHEMBL17458257 | 0.74 | PIK3CD (0.68) | PIK3CD | |
| SCHEMBL17458260 | 0.74 | PIK3CD (0.68) | PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3160960-B1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | GILEAD SCIENCES INC (US) | 2021-10-13 | — | — | EP | disclosed |