Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 18/20 | 0.85 |
| ▸ | PIK3R2 | O00459 | 2/20 | 0.65 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.60 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.59 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.58 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17458324 | 0.92 | PIK3CD (1.00) | PIK3CDPIK3R2PIK3CB | |
| SCHEMBL19346921 | 0.92 | PIK3CD (1.00) | PIK3CDPIK3R2PIK3CB | |
| SCHEMBL17458313 | 0.86 | PIK3CD (1.00) | PIK3CDPIK3R2PIK3CB | |
| SCHEMBL17458053 | 0.86 | PIK3CD (1.00) | PIK3CDPIK3R2PIK3CB | |
| SCHEMBL17458158 | 0.81 | PIK3CD (1.00) | PIK3CDPIK3R2PIK3CBPIK3R1 | |
| SCHEMBL17458162 | 0.81 | PIK3CD (1.00) | PIK3CDPIK3R2PIK3CBPIK3R1 | |
| SCHEMBL17458212 | 0.80 | PIK3CD (1.00) | PIK3CDPIK3R2PIK3R1 | |
| SCHEMBL17457975 | 0.80 | PIK3CD (1.00) | PIK3CDPIK3R2PIK3CBPIK3R1PIK3CA | |
| SCHEMBL15816847 | 0.80 | PIK3CD (0.79) | PIK3CDPIK3CBPIK3R1PIK3CAPIK3CG | |
| SCHEMBL15840583 | 0.80 | PIK3CD (0.76) | PIK3CDPIK3CBPIK3R1PIK3CAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3160960-B1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | GILEAD SCIENCES INC (US) | 2021-10-13 | — | — | EP | disclosed |