Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 7/20 | 0.35 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.30 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30803726 | 1.00 | SCN9A (0.35) | SCN9ATBK1MAP4K1 | |
| SCHEMBL22042499 | 1.00 | SCN9A (0.35) | SCN9ATBK1MAP4K1 | |
| SCHEMBL23904943 | 0.86 | SCN9A (0.36) | SCN9A | |
| SCHEMBL30803734 | 0.84 | LRRK2 (0.31) | — | |
| SCHEMBL22042421 | 0.84 | LRRK2 (0.31) | — | |
| SCHEMBL22084047 | 0.84 | LRRK2 (0.31) | — | |
| SCHEMBL28930634 | 0.83 | HTR2A (0.33) | SCN9A | |
| SCHEMBL22042400 | 0.82 | LRRK2 (0.30) | — | |
| SCHEMBL22084051 | 0.82 | LRRK2 (0.30) | — | |
| SCHEMBL30803731 | 0.82 | LRRK2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892278-B1 | CYCLOALKANE-1,3-DIAMINE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2024-02-28 | — | — | EP | disclosed |
| EP-3892278-A1 | CYCLOALKANE-1,3-DIAMINE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2021-10-13 | — | — | EP | disclosed |