Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.54 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22042577 | 1.00 | BTK (0.54) | BTKKDM1AMAOBNFKB1NFKB2 | |
| SCHEMBL30747447 | 0.90 | BTK (0.50) | BTKKDM1AMAOBNFKB1NFKB2 | |
| SCHEMBL3578826 | 0.90 | BTK (0.57) | BTKKDM1AMAOBNFKB1NFKB2 | |
| SCHEMBL18209040 | 0.90 | BTK (0.57) | BTKKDM1AMAOBNFKB1NFKB2 | |
| SCHEMBL15777845 | 0.89 | BTK (0.61) | BTKKDM1AMAOBNFKB1NFKB2 | |
| SCHEMBL23912320 | 0.88 | BTK (0.54) | BTKKDM1AMAOBNFKB1NFKB2 | |
| SCHEMBL23912332 | 0.88 | BTK (0.43) | BTKKDM1AMAOBNFKB1NFKB2 | |
| SCHEMBL24226870 | 0.88 | BTK (0.43) | BTKKDM1AMAOBNFKB1NFKB2 | |
| SCHEMBL31235109 | 0.87 | BTK (0.46) | BTKKDM1AMAOBNFKB1NFKB2 | |
| SCHEMBL22042611 | 0.85 | BTK (0.51) | BTKKDM1AMAOBNFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892278-A1 | CYCLOALKANE-1,3-DIAMINE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2021-10-13 | — | — | EP | disclosed |