Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | MITF | O75030 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | UBE2N | P61088 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22825444 | 0.91 | PTGER1 (0.33) | SMN1; SMN2RAB9ANPC1KMT2AALDH1A1 | |
| SCHEMBL21786618 | 0.91 | SMN1; SMN2 (0.38) | SMN1; SMN2RAB9ANPC1KMT2AALDH1A1 | |
| SCHEMBL21786493 | 0.87 | PTGER1 (0.39) | SMN1; SMN2KMT2AALDH1A1MEN1TBXA2R | |
| SCHEMBL23913034 | 0.86 | PTGDR2 (0.30) | — | |
| SCHEMBL21786542 | 0.85 | USP7 (0.35) | TBXA2RPTGER1HTR2AHTR2CCCR5 | |
| SCHEMBL21786448 | 0.84 | CYP11B1 (0.39) | RAB9AKMT2AALDH1A1MEN1TBXA2R | |
| SCHEMBL21786446 | 0.82 | PTGER1 (0.40) | SMN1; SMN2RAB9AKMT2APTGER1MAPT | |
| SCHEMBL21786420 | 0.82 | PTPN1 (0.40) | SMN1; SMN2KMT2AALDH1A1MEN1PTGER1 | |
| SCHEMBL21786590 | 0.82 | NPSR1 (0.36) | SMN1; SMN2KMT2AALDH1A1MEN1PTGER1 | |
| SCHEMBL23913056 | 0.81 | TBXA2R (0.35) | SMN1; SMN2RAB9ANPC1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11142504-B2 | Substituted heterocycles as c-MYC targeting agents | NORTHWESTERN UNIVERSITY (US) | 2021-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11142504-B2 | Substituted heterocycles as c-MYC targeting agents | MYC, MYCBP, MYCBP2 | SMN1; SMN2 4195/4885RAB9A 2795/4885NPC1 2687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.