Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL2391326

O=S(=O)(O)C(F)(F)F.[Ir].c1ccc(-c2ccccn2)cc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.47
TRPV1 Q8NER1 2/20 0.45
KAT6A Q92794 4/20 0.44
KDM4E B2RXH2 3/20 0.42
LMNA P02545 2/20 0.42
CYP1A2 P05177 1/20 0.42
POLB P06746 1/20 0.42
CCR1 P32246 1/20 0.42
CCR5 P51681 1/20 0.42
CCR8 P51685 1/20 0.42
METAP1 P53582 1/20 0.42
BLM P54132 1/20 0.42
HIF1A Q16665 1/20 0.42
DOHH Q9BU89 1/20 0.42
P4HTM Q9NXG6 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
DHODH Q02127 1/20 0.41
PDK2 Q15119 1/20 0.41
NPC1 O15118 1/20 0.41
MAPT P10636 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dipyridyl SCHEMBL15796588 0.88 KDM4E (0.56) CYP2A6TRPV1KDM4ELMNACYP1A2
Trifluoromethanesulfonic Acid SCHEMBL2391328 0.83 CYP2A6 (0.47) CYP2A6TRPV1KAT6AKDM4ELMNA
Trifluoromethanesulfonic Acid SCHEMBL2391337 0.83 CYP2A6 (0.47) CYP2A6TRPV1KAT6AKDM4ELMNA
Trifluoromethanesulfonic Acid SCHEMBL29983374 0.81 KDM4E (0.43) KDM4ELMNACYP1A2POLBCCR1
Trifluoromethanesulfonic Acid SCHEMBL14655597 0.80 CYP2A6 (0.51) CYP2A6KAT6AKDM4ELMNAPOLB
SCHEMBL301762 0.80 KDM4E (0.65) CYP2A6KDM4ELMNACYP1A2POLB
SCHEMBL354271 0.80 KDM4E (0.65) CYP2A6KDM4ELMNACYP1A2POLB
SCHEMBL3985205 0.80 KDM4E (0.65) CYP2A6KDM4ELMNACYP1A2POLB
SCHEMBL6831244 0.80 KDM4E (0.65) CYP2A6KDM4ELMNACYP1A2POLB
SCHEMBL51343 0.80 KDM4E (0.65) CYP2A6KDM4ELMNACYP1A2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106366130-B Phosphorescent material 通用显示公司 2021-07-09 CN disclosed
CN-106366130-A Phosphorescent materials 通用显示公司 2017-02-01 CN disclosed
US-9540329-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-01-10 US disclosed
CN-102858910-B phosphorescent material 通用显示公司 2016-09-14 CN disclosed
US-9175211-B2 Phosphorescent materials UNIVERSAL DISPLAY CORPORATION (US) 2015-11-03 US disclosed
EP-2542644-B1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORP (US) 2015-09-09 EP disclosed
US-20140021447-A1 Diarylamino Substituted Metal Complexes UNIVERSAL DISPLAY CORPORATION (US) 2014-01-23 US disclosed
EP-2542644-A1 PHOSPHORESCENT MATERIALS Universal Display Corporation (US) 2013-01-09 EP disclosed
CN-102858910-A Phosphorescent material UNIVERSAL DISPLAY CORP 2013-01-02 CN disclosed
WO-2011109042-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2011-09-09 WO disclosed
US-20110215710-A1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2011-09-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140021447-A1 Diarylamino Substituted Metal Complexes OCIAD1, OXA1L, OCIAD2 CYP2A6 3108/4885TRPV1 781/4885KAT6A 1766/4885
US-20110215710-A1 PHOSPHORESCENT MATERIALS NUDC, P2RY4, P2RY6 CYP2A6 2761/4885TRPV1 156/4885KAT6A 4320/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.