Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 14/20 | 0.63 |
| ▸ | SCN9A | Q15858 | 8/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20115587 | 0.87 | SCN9A (0.63) | SCN5ASCN9ACYP3A4 | |
| SCHEMBL20115778 | 0.84 | SCN5A (0.54) | SCN5ASCN9ACYP3A4 | |
| SCHEMBL23913154 | 0.84 | SCN5A (0.65) | SCN5ASCN9ACYP3A4 | |
| SCHEMBL20115593 | 0.81 | SCN5A (0.46) | SCN5ASCN9ACYP3A4 | |
| SCHEMBL20115542 | 0.81 | SCN5A (0.65) | SCN5ASCN9ACYP3A4 | |
| SCHEMBL20115553 | 0.80 | CYP3A4 (0.64) | SCN5ASCN9ACYP3A4 | |
| SCHEMBL20115628 | 0.79 | SCN9A (0.66) | SCN5ASCN9ACYP3A4 | |
| SCHEMBL20115636 | 0.79 | SCN5A (0.65) | SCN5ASCN9ACYP3A4 | |
| SCHEMBL23913399 | 0.78 | SCN9A (0.65) | SCN5ASCN9ACYP3A4 | |
| SCHEMBL22592995 | 0.78 | SCN9A (0.43) | SCN5ASCN9ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3532462-B1 | ACYL SULFONAMIDE NAV1.7 INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2021-10-13 | — | — | EP | disclosed |