Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 15/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CMA1 | P23946 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23914696 | 0.94 | S1PR2 (0.64) | S1PR2CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL23915204 | 0.93 | S1PR2 (0.77) | S1PR2CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL23909050 | 0.92 | S1PR2 (0.77) | S1PR2TSHRCMA1 | |
| SCHEMBL23914601 | 0.91 | S1PR2 (0.66) | S1PR2CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL23914698 | 0.91 | S1PR2 (0.64) | S1PR2CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL23914694 | 0.90 | S1PR2 (0.76) | S1PR2CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL23914693 | 0.90 | S1PR2 (0.82) | S1PR2CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL23914855 | 0.90 | S1PR2 (0.77) | S1PR2CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL23914607 | 0.89 | S1PR2 (0.77) | S1PR2CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL23915077 | 0.89 | S1PR2 (0.83) | S1PR2TSHRCMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3649119-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GALAPAGOS NV (BE) | 2021-11-03 | — | — | EP | disclosed |
| US-20210315893-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GILEAD SCIENCES, INC. | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210315893-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | S1PR1, S1PR3, S1PR2 | S1PR2 3/4885CYP1A2 1079/4885CYP3A4 3508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.