Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23908978 | 0.88 | S1PR2 (0.51) | S1PR2MAPTSMN1; SMN2GAAKDM4E | |
| SCHEMBL23914585 | 0.77 | S1PR2 (0.68) | S1PR2MAPTSMN1; SMN2GAAKDM4E | |
| SCHEMBL23908890 | 0.77 | S1PR2 (0.66) | S1PR2MAPTSMN1; SMN2GAAKDM4E | |
| SCHEMBL23908771 | 0.76 | S1PR2 (0.50) | S1PR2NPSR1TDP1 | |
| SCHEMBL23908732 | 0.73 | S1PR2 (0.71) | S1PR2MAPTSMN1; SMN2GAAKDM4E | |
| SCHEMBL23908792 | 0.73 | S1PR2 (0.63) | S1PR2MAPTSMN1; SMN2GAAKDM4E | |
| SCHEMBL23909035 | 0.73 | S1PR2 (0.58) | S1PR2MAPTSMN1; SMN2GAAKDM4E | |
| SCHEMBL23908842 | 0.72 | S1PR2 (0.79) | S1PR2MAPTSMN1; SMN2GAAKDM4E | |
| SCHEMBL23914932 | 0.70 | MAPT (0.58) | S1PR2MAPTSMN1; SMN2GAAPOLB | |
| SCHEMBL23915510 | 0.67 | S1PR2 (0.58) | S1PR2MAPTSMN1; SMN2GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210315893-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GILEAD SCIENCES, INC. | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210315893-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | S1PR1, S1PR3, S1PR2 | S1PR2 3/4885MAPT 4876/4885SMN1; SMN2 2920/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.