Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 3/20 | 0.50 |
| ▸ | BTK | Q06187 | 3/20 | 0.50 |
| ▸ | ABL1 | P00519 | 13/20 | 0.48 |
| ▸ | EGFR | P00533 | 12/20 | 0.48 |
| ▸ | SRC | P12931 | 11/20 | 0.48 |
| ▸ | ABL2 | P42684 | 11/20 | 0.48 |
| ▸ | LCK | P06239 | 5/20 | 0.48 |
| ▸ | IGF1R | P08069 | 4/20 | 0.48 |
| ▸ | JAK2 | O60674 | 3/20 | 0.48 |
| ▸ | INSR | P06213 | 3/20 | 0.48 |
| ▸ | RET | P07949 | 3/20 | 0.48 |
| ▸ | KIT | P10721 | 3/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.48 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.48 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.48 |
| ▸ | KDR | P35968 | 3/20 | 0.48 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.48 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.48 |
| ▸ | NPM1 | P06748 | 2/20 | 0.48 |
| ▸ | CSF1R | P07333 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16654148 | 0.85 | PIK3CD (0.67) | PIK3CDBTKABL1EGFRSRC | |
| Hydrochloric Acid SCHEMBL23908623 | 0.85 | PIK3CD (0.66) | PIK3CDBTKABL1EGFRSRC | |
| SCHEMBL16655504 | 0.84 | PIK3CD (0.55) | PIK3CDBTKABL1EGFRSRC | |
| SCHEMBL16654718 | 0.83 | PIK3CD (0.52) | PIK3CDBTKABL1EGFRSRC | |
| SCHEMBL16654294 | 0.81 | PIK3CD (0.52) | PIK3CDBTKABL1EGFRSRC | |
| SCHEMBL16654722 | 0.80 | PIK3CD (0.61) | PIK3CDBTKABL1EGFRSRC | |
| SCHEMBL31060265 | 0.79 | PIK3CD (0.66) | PIK3CDBTKABL1EGFRSRC | |
| SCHEMBL16655471 | 0.79 | PIK3CD (0.66) | PIK3CDBTKABL1EGFRSRC | |
| SCHEMBL16655527 | 0.78 | PIK3CD (0.55) | PIK3CDBTKABL1EGFRSRC | |
| SCHEMBL16655704 | 0.77 | PIK3CD (0.66) | PIK3CDBTKABL1EGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317140-A1 | Heterocyclic Compounds and Methods of Use | MEDIVATION TECHNOLOGIES, INC. (US) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317140-A1 | Heterocyclic Compounds and Methods of Use | BTK, PIK3CD, PIK3CB | PIK3CD 2/4885BTK 1/4885ABL1 62/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.