Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 1/20 | 0.57 |
| ▸ | TGFBR1 | P36897 | 9/20 | 0.51 |
| ▸ | SRC | P12931 | 5/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | ABL1 | P00519 | 2/20 | 0.50 |
| ▸ | HCK | P08631 | 2/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.50 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.50 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.50 |
| ▸ | PRKDC | P78527 | 1/20 | 0.50 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | TEK | Q02763 | 1/20 | 0.47 |
| ▸ | ATR | Q13535 | 1/20 | 0.47 |
| ▸ | FRK | P42685 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23917211 | 0.83 | PIK3CD (0.55) | TGFBR1SRCABL1HCKPIK3CD | |
| SCHEMBL16655730 | 0.81 | ATR (0.70) | SRCABL1HCKPIK3CDEGFR | |
| SCHEMBL23917484 | 0.80 | PIK3CD (0.50) | TGFBR1SRCKCNH2ABL1HCK | |
| SCHEMBL17725992 | 0.73 | FYN (1.00) | FYNSRCABL1HCKPIK3CD | |
| SCHEMBL16655658 | 0.73 | ATR (0.71) | SRCPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL23917469 | 0.73 | PIK3CD (0.45) | TGFBR1SRCKCNH2ABL1HCK | |
| SCHEMBL16655596 | 0.73 | PIK3CD (0.65) | SRCABL1HCKPIK3CDEGFR | |
| SCHEMBL130427 | 0.72 | PIK3CD (0.72) | FYNSRCABL1HCKPIK3CD | |
| SCHEMBL23917452 | 0.72 | PIK3CD (0.55) | SRCABL1HCKPIK3CDEGFR | |
| SCHEMBL16655966 | 0.69 | BTK (0.66) | SRCPIK3CDLCKTEKATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317140-A1 | Heterocyclic Compounds and Methods of Use | MEDIVATION TECHNOLOGIES, INC. (US) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317140-A1 | Heterocyclic Compounds and Methods of Use | BTK, PIK3CD, PIK3CB | FYN 192/4885TGFBR1 3390/4885SRC 92/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.