Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.63 |
| ▸ | MEN1 | O00255 | 5/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2103705 | 0.80 | KMT2A (0.64) | KMT2AMEN1L3MBTL1TSHRMAPK1 | |
| SCHEMBL1033548 | 0.78 | KMT2A (0.66) | KMT2AMEN1L3MBTL1TSHRMAPK1 | |
| SCHEMBL29843194 | 0.78 | KMT2A (0.66) | KMT2AMEN1L3MBTL1TSHRMAPK1 | |
| SCHEMBL3007964 | 0.78 | KMT2A (0.66) | KMT2AMEN1L3MBTL1TSHRMAPK1 | |
| SCHEMBL1265953 | 0.78 | KMT2A (1.00) | KMT2AMEN1L3MBTL1TSHRAKR1C3 | |
| SCHEMBL1265951 | 0.78 | KMT2A (1.00) | KMT2AMEN1L3MBTL1TSHRAKR1C3 | |
| SCHEMBL19122497 | 0.77 | KMT2A (0.66) | KMT2AMEN1L3MBTL1TSHRMAPK1 | |
| SCHEMBL2103706 | 0.77 | KMT2A (0.64) | KMT2AMEN1L3MBTL1TSHRMAPK1 | |
| SCHEMBL2815639 | 0.77 | KMT2A (0.64) | KMT2AMEN1L3MBTL1TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL27678137 | 0.77 | KMT2A (0.64) | KMT2AMEN1L3MBTL1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317140-A1 | Heterocyclic Compounds and Methods of Use | MEDIVATION TECHNOLOGIES, INC. (US) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317140-A1 | Heterocyclic Compounds and Methods of Use | BTK, PIK3CD, PIK3CB | KMT2A 1213/4885MEN1 1754/4885L3MBTL1 1969/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.