Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23393949 | 0.94 | TUBB1 (0.39) | TUBB1 | |
| SCHEMBL23394081 | 0.91 | TUBB1 (0.38) | TUBB1MTNR1AMTNR1B | |
| SCHEMBL23394103 | 0.89 | TUBB1 (0.40) | TUBB1MTNR1AMTNR1B | |
| SCHEMBL57117 | 0.89 | TUBB1 (0.41) | TUBB1 | |
| SCHEMBL14567799 | 0.89 | TUBB1 (0.41) | TUBB1 | |
| SCHEMBL23394051 | 0.89 | TUBB1 (0.41) | TUBB1 | |
| SCHEMBL23394087 | 0.86 | TUBB1 (0.38) | TUBB1 | |
| SCHEMBL17992609 | 0.85 | TUBB1 (0.57) | TUBB1 | |
| SCHEMBL17992678 | 0.85 | TUBB1 (0.57) | TUBB1 | |
| SCHEMBL17992582 | 0.85 | TUBB1 (0.57) | TUBB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892305-A1 | HEMIASTERLIN DERIVATIVES FOR CONJUGATION AND THERAPY | Sutro Biopharma, Inc. (US) | 2021-10-13 | — | — | EP | disclosed |