⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14967979 | 0.84 | — | — | |
| SCHEMBL1106523 | 0.82 | — | — | |
| SCHEMBL11201426 | 0.78 | — | — | |
| SCHEMBL16044897 | 0.78 | — | — | |
| SCHEMBL149338 | 0.78 | — | — | |
| SCHEMBL24568176 | 0.78 | KDM4E (0.49) | — | |
| SCHEMBL23269830 | 0.78 | — | — | |
| SCHEMBL23663784 | 0.78 | KDM4E (0.49) | — | |
| SCHEMBL4200299 | 0.78 | — | — | |
| SCHEMBL25650181 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892305-A1 | HEMIASTERLIN DERIVATIVES FOR CONJUGATION AND THERAPY | Sutro Biopharma, Inc. (US) | 2021-10-13 | — | — | EP | disclosed |