Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PDE9A | O76083 | 14/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PDE1C | Q14123 | 3/20 | 0.41 |
| ▸ | PLK4 | O00444 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31051051 | 1.00 | KDM4E (0.42) | KDM4EPDE9AKMT2APDE1CPLK4 | |
| SCHEMBL2357706 | 0.84 | KDM4E (0.43) | KDM4EPDE9AKMT2APDE1C | |
| SCHEMBL13251787 | 0.82 | KDM4E (0.44) | KDM4EPDE9AKMT2APDE1CPLK4 | |
| SCHEMBL31403549 | 0.81 | KDM4E (0.41) | KDM4EPDE9AKMT2APDE1CPLK4 | |
| SCHEMBL31403622 | 0.81 | ADORA2A (0.46) | KDM4EPDE9AKMT2APDE1C | |
| SCHEMBL24500614 | 0.79 | KDM4E (0.42) | KDM4EPDE9AKMT2APDE1C | |
| SCHEMBL30095720 | 0.79 | KDM4E (0.40) | KDM4EPDE9AKMT2APDE1C | |
| SCHEMBL29174768 | 0.79 | KDM4E (0.40) | KDM4EPDE9AKMT2APDE1C | |
| SCHEMBL21282841 | 0.79 | KDM4E (0.40) | KDM4EPDE9AKMT2APDE1C | |
| SCHEMBL30095819 | 0.78 | KDM4E (0.50) | KDM4EPDE9AKMT2APDE1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117529315-A | Imidazole-containing ALK2 kinase inhibitors | 生物水晶制药公司 | 2024-02-06 | — | — | CN | disclosed |
| EP-3892622-A1 | COMPOUNDS HAVING PDE9A INHIBITORY ACTIVITY, AND PHARMACEUTICAL USES THEREOF | Korea Research Institute of Chemical Technology (KR) | 2021-10-13 | — | — | EP | disclosed |