Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | COMT | P21964 | 2/20 | 0.38 |
| ▸ | CDC25A | P30304 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | CDC25C | P30307 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4322190 | 0.90 | NAPRT (0.61) | NAPRTSMN1; SMN2POLBMEN1LMNA | |
| SCHEMBL23907035 | 0.79 | NAPRT (0.80) | NAPRTFAAHMGLLAPPCOMT | |
| SCHEMBL4341101 | 0.78 | NAPRT (0.62) | NAPRTSMN1; SMN2POLBMEN1LMNA | |
| SCHEMBL10998478 | 0.76 | MAPT (0.48) | SMN1; SMN2POLBMAPTMEN1LMNA | |
| SCHEMBL5421935 | 0.74 | NAPRT (0.57) | NAPRTSMN1; SMN2MAPTMEN1LMNA | |
| SCHEMBL17035275 | 0.74 | NAPRT (0.62) | NAPRTSMN1; SMN2POLBMAPTMEN1 | |
| SCHEMBL5482874 | 0.74 | NAPRT (0.49) | NAPRTSMN1; SMN2POLBMAPTMEN1 | |
| SCHEMBL2743024 | 0.71 | NAPRT (0.53) | NAPRTSMN1; SMN2POLBMAPTLMNA | |
| SCHEMBL10269246 | 0.71 | NAPRT (0.53) | NAPRTPOLBLMNA | |
| SCHEMBL5426155 | 0.70 | NAPRT (0.71) | NAPRTSMN1; SMN2POLBMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892734-A1 | SCREENING METHODS AND THERAPEUTIC APPLICATIONS BASED ON BACTERIAL MOTILITY INHIBITION | Ludwig-Maximilians-Universität München (DE) | 2021-10-13 | — | — | EP | disclosed |