Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 16/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25582670 | 1.00 | ELANE (0.44) | ELANEKMT2AATMALDH1A1LMNA | |
| SCHEMBL16803381 | 0.90 | ELANE (0.51) | ELANEKMT2AATMALDH1A1LMNA | |
| SCHEMBL15625536 | 0.90 | ELANE (0.51) | ELANEKMT2AATMALDH1A1LMNA | |
| SCHEMBL21173252 | 0.90 | ELANE (0.42) | ELANEKMT2AATM | |
| SCHEMBL21254274 | 0.90 | ELANE (0.42) | ELANEKMT2AATM | |
| SCHEMBL25908219 | 0.90 | ELANE (0.45) | ELANEKMT2A | |
| SCHEMBL18699565 | 0.88 | ELANE (0.41) | ELANEKMT2AATM | |
| SCHEMBL22173868 | 0.88 | ELANE (0.41) | ELANE | |
| SCHEMBL21254284 | 0.87 | ELANE (0.44) | ELANEKMT2AATMLMNA | |
| SCHEMBL23397388 | 0.87 | POLB (0.38) | ELANEKMT2AATMALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023198671-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2023-10-19 | — | — | WO | disclosed |
| EP-3892706-A2 | LIQUID-CRYSTALLINE MEDIUM | Merck Patent GmbH (DE) | 2021-10-13 | — | — | EP | disclosed |