Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.43 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.43 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2389760 | 0.83 | HTR2C (0.64) | HTR2CCACNA1GCACNA1HCACNA1IMEN1 | |
| SCHEMBL8606286 | 0.74 | HTR2C (0.70) | HTR2CCACNA1GCACNA1HCACNA1IMEN1 | |
| SCHEMBL16467962 | 0.72 | HTR2C (0.76) | HTR2CCACNA1GCACNA1HCACNA1IMEN1 | |
| SCHEMBL3652770 | 0.72 | HTR2C (0.76) | HTR2CCACNA1GCACNA1HCACNA1IMEN1 | |
| SCHEMBL10466611 | 0.72 | HTR2C (0.62) | HTR2CCACNA1GCACNA1HCACNA1IMEN1 | |
| SCHEMBL29587713 | 0.72 | HTR2C (0.59) | HTR2CCACNA1GCACNA1HCACNA1IMEN1 | |
| SCHEMBL30523560 | 0.71 | HTR2C (0.55) | HTR2CCACNA1GCACNA1HCACNA1IMEN1 | |
| SCHEMBL25843950 | 0.71 | HTR2C (0.55) | HTR2CCACNA1GCACNA1HCACNA1IMEN1 | |
| SCHEMBL25843953 | 0.71 | HTR2C (0.55) | HTR2CCACNA1GCACNA1HCACNA1IMEN1 | |
| SCHEMBL10387195 | 0.71 | HTR2C (0.51) | HTR2CMEN1KMT2ANPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8013008-B2 | Cyclic amine compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-09-06 | — | — | US | disclosed |