Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 4/20 | 0.46 |
| ▸ | KDR | P35968 | 4/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 2/20 | 0.40 |
| ▸ | FLT3 | P36888 | 2/20 | 0.40 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | HCK | P08631 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29743061 | 1.00 | CHEK1 (0.46) | CHEK1KDRLCKKITFLT3 | |
| SCHEMBL29743069 | 0.88 | CHEK1 (0.43) | CHEK1KDRLCKSYKHCK | |
| SCHEMBL23921962 | 0.88 | KDR (0.46) | KDRMAP3K12 | |
| SCHEMBL23921961 | 0.88 | KDR (0.48) | CHEK1KDRLCKKITFLT3 | |
| SCHEMBL29743067 | 0.87 | LCK (0.42) | CHEK1KDRLCKHCKBTK | |
| SCHEMBL28893696 | 0.86 | CHEK1 (0.42) | CHEK1KDRLCKKITFLT3 | |
| SCHEMBL29838449 | 0.86 | KDR (0.44) | CHEK1KDRLCKKITFLT3 | |
| SCHEMBL22206182 | 0.85 | JAK3 (0.45) | CHEK1KDRLCKALKHCK | |
| SCHEMBL20908740 | 0.83 | EGFR (0.52) | HCKBTKJAK2JAK3 | |
| SCHEMBL22215290 | 0.83 | KDR (0.44) | CHEK1KDRKITFLT3SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11149019-B2 | Phenylpyridine derivative and pharmaceutical composition comprising the same | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2021-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11149019-B2 | Phenylpyridine derivative and pharmaceutical composition comprising the same | DPYD, PDCD5, PDCD1 | CHEK1 1981/4885KDR 3048/4885LCK 283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.