Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.45 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.45 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.45 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | PPIA | P62937 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2393734 | 0.93 | EPHX2 (0.56) | EPHX2MEN1KMT2AMAPTLMNA | |
| SCHEMBL11885104 | 0.88 | EPHX2 (0.51) | EPHX2MEN1KMT2AMAPTLMNA | |
| SCHEMBL11885023 | 0.87 | MEN1 (0.55) | EPHX2MEN1KMT2AMAPTLMNA | |
| SCHEMBL11885165 | 0.85 | EPHX2 (0.52) | EPHX2MEN1KMT2AMAPTLMNA | |
| SCHEMBL11885148 | 0.85 | MEN1 (0.49) | EPHX2MEN1KMT2AMAPTLMNA | |
| SCHEMBL11885106 | 0.84 | EPHX2 (0.47) | EPHX2MEN1KMT2AMAPTLMNA | |
| SCHEMBL11885020 | 0.84 | EPHX2 (0.46) | EPHX2MEN1KMT2AMAPTLMNA | |
| SCHEMBL11885170 | 0.83 | KMT2A (0.50) | EPHX2MEN1KMT2AMAPTLMNA | |
| SCHEMBL11885036 | 0.82 | MEN1 (0.49) | EPHX2MEN1KMT2AMAPTLMNA | |
| SCHEMBL14996419 | 0.82 | SMN1; SMN2 (0.51) | MEN1KMT2AMAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2195302-B1 | INSECTICIDAL SUBSTITUTED AZINYL DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2015-02-18 | — | — | EP | disclosed |
| EP-2195302-B1 | INSECTICIDAL SUBSTITUTED AZINYL DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2015-02-18 | — | — | EP | disclosed |
| US-8507671-B2 | Insecticidal substituted azinyl derivatives | DOW AGROSCIENCES LLC (US) | 2013-08-13 | — | — | US | disclosed |
| US-8507671-B2 | Insecticidal substituted azinyl derivatives | DOW AGROSCIENCES LLC (US) | 2013-08-13 | — | — | US | disclosed |
| US-8507671-B2 | Insecticidal substituted azinyl derivatives | DOW AGROSCIENCES LLC (US) | 2013-08-13 | — | — | US | disclosed |
| US-8455649-B2 | Insecticidal substituted azinyl derivatives | DOW AGROSCIENCES, LLC (US) | 2013-06-04 | — | — | US | disclosed |
| US-8455649-B2 | Insecticidal substituted azinyl derivatives | DOW AGROSCIENCES, LLC (US) | 2013-06-04 | — | — | US | disclosed |
| US-8455649-B2 | Insecticidal substituted azinyl derivatives | DOW AGROSCIENCES, LLC (US) | 2013-06-04 | — | — | US | disclosed |
| US-20120190683-A1 | INSECTICIDAL SUBSTITUTED AZINYL DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120190683-A1 | INSECTICIDAL SUBSTITUTED AZINYL DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120190683-A1 | INSECTICIDAL SUBSTITUTED AZINYL DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120190684-A1 | INSECTICIDAL SUBSTITUTED AZINYL DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120190684-A1 | INSECTICIDAL SUBSTITUTED AZINYL DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2012-07-26 | — | — | US | disclosed |
| US-8013154-B2 | Insecticidal substituted azinyl derivatives | CORTEVA AGRISCIENCE LLC | 2011-09-06 | — | — | US | disclosed |
| US-8013154-B2 | Insecticidal substituted azinyl derivatives | CORTEVA AGRISCIENCE LLC | 2011-09-06 | — | — | US | disclosed |
| US-8013154-B2 | Insecticidal substituted azinyl derivatives | CORTEVA AGRISCIENCE LLC | 2011-09-06 | — | — | US | disclosed |
| WO-2009048752-A2 | INSECTICIDAL SUBSTITUTED AZINYL DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2009-04-16 | — | — | WO | disclosed |
| US-20090093486-A1 | INSECTICIDAL SUBSTITUTED AZINYL DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2009-04-09 | — | — | US | disclosed |
| US-20090093486-A1 | INSECTICIDAL SUBSTITUTED AZINYL DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2009-04-09 | — | — | US | disclosed |
| US-20090093486-A1 | INSECTICIDAL SUBSTITUTED AZINYL DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2009-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120190683-A1 | INSECTICIDAL SUBSTITUTED AZINYL DERIVATIVES | AZI2, UNC119, NISCH | EPHX2 2755/4885MEN1 3633/4885KMT2A 1033/4885 |
| US-20090093486-A1 | INSECTICIDAL SUBSTITUTED AZINYL DERIVATIVES | AZI2, UNC119, NISCH | EPHX2 2755/4885MEN1 3633/4885KMT2A 1033/4885 |
| US-20120190684-A1 | INSECTICIDAL SUBSTITUTED AZINYL DERIVATIVES | AZI2, UNC119, NISCH | EPHX2 2755/4885MEN1 3633/4885KMT2A 1033/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.