Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 20/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18623735 | 1.00 | LRRK2 (0.54) | LRRK2 | |
| SCHEMBL18623743 | 0.87 | LRRK2 (0.72) | LRRK2 | |
| SCHEMBL18623738 | 0.87 | LRRK2 (0.72) | LRRK2 | |
| SCHEMBL23922642 | 0.87 | LRRK2 (0.72) | LRRK2 | |
| SCHEMBL18623752 | 0.83 | LRRK2 (0.70) | LRRK2 | |
| SCHEMBL18658821 | 0.81 | LRRK2 (0.51) | LRRK2 | |
| SCHEMBL18659005 | 0.81 | LRRK2 (0.51) | LRRK2 | |
| SCHEMBL18606322 | 0.76 | LRRK2 (0.79) | LRRK2 | |
| SCHEMBL18623747 | 0.72 | LRRK2 (0.66) | LRRK2 | |
| SCHEMBL18658802 | 0.72 | LRRK2 (0.66) | LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3350178-B1 | NOVEL IMIDAZO [4,5-C]QUINOLINE AND IMIDAZO [4,5-C][1,5]NAPHTHYRIDINE DERIVATIVES AS LRRK2 INHIBITORS | PFIZER (US) | 2021-10-20 | — | — | EP | disclosed |