SCHEMBL23922931

SCHEMBL23922931

O=C1C(=Cc2ccc(Cl)cc2)CCC1=Cc1ccc(Cl)cc1

nearest known ligand 0.67

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.67
CYP1A2 P05177 7/20 0.64
HSD11B1 P28845 3/20 0.64
CYP2C9 P11712 2/20 0.64
CYP3A4 P08684 1/20 0.64
AKR1C3 P42330 1/20 0.63
AKR1C1 Q04828 1/20 0.63
EGFR P00533 1/20 0.59
F3 P13726 2/20 0.55
F2 P00734 2/20 0.55
F10 P00742 2/20 0.55
ACHE P22303 2/20 0.55
PTGS2 P35354 1/20 0.55
PAX8 Q06710 1/20 0.54
PLAU P00749 1/20 0.50
PLAT P00750 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11817550 0.92 AKR1C3 (0.76) MAOBCYP1A2HSD11B1CYP2C9CYP3A4
SCHEMBL11841756 0.92 AKR1C3 (0.70) MAOBCYP1A2HSD11B1CYP2C9AKR1C3
SCHEMBL11817554 0.92 AKR1C3 (0.76) MAOBCYP1A2HSD11B1CYP2C9CYP3A4
SCHEMBL11841748 0.92 AKR1C3 (0.70) MAOBCYP1A2HSD11B1CYP2C9AKR1C3
SCHEMBL1524524 0.87 MAOB (0.58) MAOBCYP1A2HSD11B1CYP2C9CYP3A4
SCHEMBL1524522 0.87 MAOB (0.58) MAOBCYP1A2HSD11B1CYP2C9CYP3A4
SCHEMBL21612281 0.84 AKR1C3 (0.65) MAOBCYP1A2HSD11B1CYP2C9CYP3A4
SCHEMBL21612285 0.84 AKR1C3 (0.65) MAOBCYP1A2HSD11B1CYP2C9CYP3A4
SCHEMBL21612283 0.84 AKR1C3 (0.65) MAOBCYP1A2HSD11B1CYP2C9CYP3A4
SCHEMBL15940019 0.84 MEN1 (0.53) MAOBCYP1A2HSD11B1CYP2C9CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12094507-B2 Hologram recording composition, hologram recording medium, diffraction optical element, and optical device, optical component, and image display device using diffraction optical element Sony Group Corporation (JP) 2024-09-17 US disclosed
EP-3896530-B1 HOLOGRAM RECORDING COMPOSITION, HOLOGRAM RECORDING MEDIUM, DIFFRACTION OPTICAL ELEMENT, AND OPTICAL DEVICE, OPTICAL COMPONENT, AND IMAGE DISPLAY DEVICE IN WHICH DIFFRACTION OPTICAL ELEMENT IS USED SONY GROUP CORP (JP) 2023-05-24 EP disclosed
CN-113168129-B Hologram recording composition, hologram recording medium, diffractive optical element, and optical device, optical member, and image display device using diffractive optical element 索尼集团公司 2022-08-05 CN disclosed
US-20220013142-A1 HOLOGRAM RECORDING COMPOSITION, HOLOGRAM RECORDING MEDIUM, DIFFRACTION OPTICAL ELEMENT, AND OPTICAL DEVICE, OPTICAL COMPONENT, AND IMAGE DISPLAY DEVICE USING DIFFRACTION OPTICAL ELEMENT Sony Group Corporation (JP) 2022-01-13 US disclosed
EP-3896530-A1 HOLOGRAM RECORDING COMPOSITION, HOLOGRAM RECORDING MEDIUM, DIFFRACTION OPTICAL ELEMENT, AND OPTICAL DEVICE, OPTICAL COMPONENT, AND IMAGE DISPLAY DEVICE IN WHICH DIFFRACTION OPTICAL ELEMENT IS USED Sony Group Corporation (JP) 2021-10-20 EP disclosed