SCHEMBL23923224

SCHEMBL23923224

CC(C)(C)OC(=O)CN(CCC(=O)ON1C(=O)c2ccccc2C1=O)C(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.35
CASP1 P29466 1/20 0.33
MDM2 Q00987 1/20 0.33
FABP5 Q01469 3/20 0.33
FABP7 O15540 2/20 0.33
EPHX2 P34913 1/20 0.32
CASP3 P42574 1/20 0.32
MDM4 O15151 1/20 0.31
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30278711 1.00 KMT2A (0.35) KMT2ACASP1MDM2FABP5FABP7
SCHEMBL22092037 0.86 KMT2A (0.39) KMT2AMDM2FABP5FABP7EPHX2
SCHEMBL30278742 0.85 KMT2A (0.47) KMT2AMDM2FABP5FABP7EPHX2
SCHEMBL22091999 0.85 KMT2A (0.47) KMT2AMDM2FABP5FABP7EPHX2
SCHEMBL12314878 0.84 KMT2A (0.41) KMT2ACASP1FABP5FABP7EPHX2
SCHEMBL7062622 0.83 KMT2A (0.42) KMT2AMDM2FABP5FABP7EPHX2
SCHEMBL29516484 0.83 KMT2A (0.42) KMT2AMDM2FABP5FABP7EPHX2
SCHEMBL25657528 0.83 KMT2A (0.39) KMT2AMDM2FABP5FABP7EPHX2
SCHEMBL25657526 0.81 KMT2A (0.40) KMT2ACASP1MDM2FABP5FABP7
SCHEMBL31000664 0.81 KMT2A (0.36) KMT2AFABP5FABP7EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230096766-A1 AMINO ACID HAVING FUNCTIONAL GROUP CAPABLE OF INTERMOLECULAR HYDROGEN BONDING, PEPTIDE COMPOUND CONTAINING SAME AND METHOD FOR PRODUCTION THEREOF CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-03-30 US disclosed
EP-3896056-A1 AMINO ACID HAVING FUNCTIONAL GROUP CAPABLE OF INTERMOLECULAR HYDROGEN BONDING, PEPTIDE COMPOUND CONTAINING SAME AND METHOD FOR PRODUCTION THEREOF CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2021-10-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230096766-A1 AMINO ACID HAVING FUNCTIONAL GROUP CAPABLE OF INTERMOLECULAR HYDROGEN BONDING, PEPTIDE COMPOUND CONTAINING SAME AND METHOD FOR PRODUCTION THEREOF VIP, DNPEP, HM13 KMT2A 3453/4885CASP1 3474/4885MDM2 3655/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.