Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 5/20 | 0.52 |
| ▸ | PPARA | Q07869 | 3/20 | 0.52 |
| ▸ | MME | P08473 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23922997 | 0.83 | FOLH1 (0.50) | FOLH1PPARGPPARAMMEMMP9 | |
| SCHEMBL21837541 | 0.82 | PPARA (0.58) | FOLH1PPARGPPARASMN1; SMN2CTSS | |
| SCHEMBL21837546 | 0.82 | PPARA (0.58) | FOLH1PPARGPPARASMN1; SMN2CTSS | |
| SCHEMBL20637864 | 0.81 | FOLH1 (0.63) | FOLH1PPARGPPARAMMESMN1; SMN2 | |
| SCHEMBL18127216 | 0.81 | FOLH1 (0.63) | FOLH1PPARGPPARAMMESMN1; SMN2 | |
| SCHEMBL16418003 | 0.81 | FOLH1 (0.63) | FOLH1PPARGPPARAMMESMN1; SMN2 | |
| SCHEMBL18555446 | 0.78 | FOLH1 (0.55) | FOLH1PPARGPPARAMMEMMP9 | |
| SCHEMBL20899650 | 0.77 | PPARA (0.82) | FOLH1PPARGPPARAMMERAB9A | |
| SCHEMBL846602 | 0.77 | MME (0.59) | MMEGPR132 | |
| SCHEMBL1942200 | 0.77 | FOLH1 (0.64) | FOLH1PPARGPPARAMMEMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3896056-A1 | AMINO ACID HAVING FUNCTIONAL GROUP CAPABLE OF INTERMOLECULAR HYDROGEN BONDING, PEPTIDE COMPOUND CONTAINING SAME AND METHOD FOR PRODUCTION THEREOF | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2021-10-20 | — | — | EP | disclosed |