Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28483715 | 1.00 | TSHR (0.46) | TSHRLMNADNM1ALDH1A1TP53 | |
| Bromide SCHEMBL28443842 | 1.00 | TSHR (0.46) | TSHRLMNADNM1ALDH1A1TP53 | |
| Bromide SCHEMBL28239199 | 1.00 | TSHR (0.46) | TSHRLMNADNM1ALDH1A1TP53 | |
| Bromide SCHEMBL28559972 | 1.00 | TSHR (0.46) | TSHRLMNADNM1ALDH1A1TP53 | |
| Bromide SCHEMBL7117275 | 1.00 | TSHR (0.46) | TSHRLMNADNM1ALDH1A1TP53 | |
| Bromide SCHEMBL11689756 | 1.00 | TSHR (0.46) | TSHRLMNADNM1ALDH1A1TP53 | |
| Bromide SCHEMBL28559975 | 1.00 | TSHR (0.46) | TSHRLMNADNM1ALDH1A1TP53 | |
| Bromide SCHEMBL28567568 | 0.98 | TSHR (0.44) | TSHRLMNADNM1ALDH1A1TP53 | |
| SCHEMBL9772649 | 0.98 | TSHR (0.47) | TSHRLMNADNM1HSP90AA1MAPT | |
| SCHEMBL27943905 | 0.98 | TSHR (0.47) | TSHRLMNADNM1HSP90AA1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114854117-B | Non-release type durable broad-spectrum antibacterial and antiviral packaging film material and preparation method thereof | 水木聚力接枝新技术(深圳)有限责任公司 | 2023-10-13 | — | — | CN | claimed |
| US-11643482-B2 | POSS modified polyacrylate fluoride-free waterproof agent and preparation method thereof | SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2023-05-09 | — | — | US | claimed |
| US-20210324116-A1 | POSS MODIFIED POLYACRYLATE FLUORIDE-FREE WATERPROOF AGENT AND PREPARATION METHOD THEREOF | SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2021-10-21 | — | — | US | claimed |
| CN-112300334-A | POSS/organosilicon modified polyacrylate fluorine-free waterproof agent and preparation method thereof | 陕西科技大学 | 2021-02-02 | — | — | CN | claimed |
| CN-114854117-B | Non-release type durable broad-spectrum antibacterial and antiviral packaging film material and preparation method thereof | 水木聚力接枝新技术(深圳)有限责任公司 | 2023-10-13 | — | — | CN | disclosed |
| US-11643482-B2 | POSS modified polyacrylate fluoride-free waterproof agent and preparation method thereof | SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2023-05-09 | — | — | US | disclosed |
| CN-112300334-B | POSS/organosilicon modified polyacrylate fluorine-free waterproof agent and preparation method thereof | 陕西科技大学 | 2022-11-11 | — | — | CN | disclosed |
| US-20210324116-A1 | POSS MODIFIED POLYACRYLATE FLUORIDE-FREE WATERPROOF AGENT AND PREPARATION METHOD THEREOF | SHAANXI UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2021-10-21 | — | — | US | disclosed |
| CN-112300334-A | POSS/organosilicon modified polyacrylate fluorine-free waterproof agent and preparation method thereof | 陕西科技大学 | 2021-02-02 | — | — | CN | disclosed |
| CN-111410712-A | POSS (polyhedral oligomeric silsesquioxane) modified polyacrylate fluorine-free waterproof agent and preparation method thereof | 陕西科技大学 | 2020-07-14 | — | — | CN | disclosed |