Ethylene Glycol

Ethylene Glycol

SCHEMBL23923625

CCCCCC[C@H]1C(=O)CC[C@H]1CC(=O)OC.OCCO

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER2 P43116 6/20 0.47
PTGER4 P35408 3/20 0.47
PTGER3 P43115 3/20 0.47
TSHR P16473 1/20 0.43
HTT P42858 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
PGR P06401 1/20 0.39
POLB P06746 1/20 0.39
MAPT P10636 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
AKR1C4 P17516 1/20 0.39
AKR1C3 P42330 1/20 0.39
AKR1C2 P52895 1/20 0.39
ABCC4 O15439 1/20 0.39
ABCB11 O95342 1/20 0.39
PRKCA P17252 4/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL22125474 1.00 PTGER2 (0.47) PTGER2PTGER4PTGER3TSHRHTT
Dihydrojasmonic Acid, Methyl Ester SCHEMBL22125491 0.99 PTGER2 (0.46) PTGER2PTGER4PTGER3TSHRHTT
Dihydrojasmonic Acid, Methyl Ester SCHEMBL23923603 0.99 PTGER2 (0.46) PTGER2PTGER4PTGER3TSHRHTT
SCHEMBL22125299 0.96 PTGER2 (0.50) PTGER2PTGER4PTGER3TSHRHTT
SCHEMBL11516292 0.96 PTGER2 (0.50) PTGER2PTGER4PTGER3TSHRHTT
SCHEMBL29785189 0.96 PTGER2 (0.50) PTGER2PTGER4PTGER3TSHRHTT
Ethylene Glycol SCHEMBL22125447 0.95 PTGER2 (0.42) PTGER2PTGER4PTGER3TSHRHTT
Ethylene Glycol SCHEMBL23923598 0.95 PTGER2 (0.42) PTGER2PTGER4PTGER3TSHRHTT
Dihydrojasmonic Acid, Methyl Ester SCHEMBL21662531 0.95 PTGER2 (0.48) PTGER2PTGER4PTGER3TSHRHTT
Dihydrojasmonic Acid, Methyl Ester SCHEMBL17517758 0.95 PTGER2 (0.48) PTGER2PTGER4PTGER3TSHRHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11339113-B2 Process for the preparation of cis-alpha,beta substituted cyclopentanones FIRMENICH SA (CH) 2022-05-24 US disclosed
US-20210323904-A1 PROCESS FOR THE PREPARATION OF CIS-ALPHA,BETA SUBSTITUTED CYCLOPENTANONES FIRMENICH SA (CH) 2021-10-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11339113-B2 Process for the preparation of cis-alpha,beta substituted cyclopentanones CYP4A11, CYP11B1, CYP51A1 PTGER2 1243/4885PTGER4 216/4885PTGER3 1113/4885
US-20210323904-A1 PROCESS FOR THE PREPARATION OF CIS-ALPHA,BETA SUBSTITUTED CYCLOPENTANONES CYP4A11, CYP11B1, CYP51A1 PTGER2 1243/4885PTGER4 216/4885PTGER3 1113/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.