Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | MGAM | O43451 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | SI | P14410 | 2/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | TPMT | P51580 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7826588 | 0.83 | SMN1; SMN2 (0.58) | KMT2ATSHRHTR2AHTR2CHTR2B | |
| SCHEMBL21057246 | 0.83 | SMN1; SMN2 (0.58) | KMT2ATSHRHTR2AHTR2CHTR2B | |
| SCHEMBL11297323 | 0.83 | KMT2A (0.49) | KMT2ATSHRHTR2AHTR2CHTR2B | |
| SCHEMBL31426193 | 0.82 | TSHR (0.50) | KMT2ATSHRHTR2AHTR2CHTR2B | |
| SCHEMBL233034 | 0.82 | TDP1 (0.56) | KMT2ATSHRHTR2AHTR2CHTR2B | |
| SCHEMBL23368020 | 0.82 | TSHR (0.67) | KMT2ATSHRHTR2AHTR2CHTR2B | |
| SCHEMBL18330954 | 0.82 | TSHR (0.67) | KMT2ATSHRHTR2AHTR2CHTR2B | |
| SCHEMBL3602820 | 0.82 | TSHR (0.50) | KMT2ATSHRHTR2AHTR2CHTR2B | |
| SCHEMBL18331136 | 0.82 | TSHR (0.50) | KMT2ATSHRHTR2AHTR2CHTR2B | |
| SCHEMBL5758294 | 0.82 | KMT2A (0.45) | KMT2ATSHRHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4136084-A1 | BCL-2 INHIBITOR | BeiGene, Ltd. (KY) | 2023-02-22 | — | — | EP | disclosed |
| WO-2021208963-A1 | BCL-2 INHIBITOR | BEIGENE, LTD. (KY) | 2021-10-21 | — | — | WO | disclosed |