SCHEMBL23925931

SCHEMBL23925931

CCCCCCCCCCCCCCCCCCOC(=O)Cc1cc2c(c(C(C)(C)C)c1)OC(=O)C2

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 6/20 0.38
NAAA Q02083 1/20 0.36
PTGS2 P35354 1/20 0.35
EPHX2 P34913 1/20 0.35
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
HSD17B10 Q99714 1/20 0.35
NLRP3 Q96P20 1/20 0.34
THRA P10827 1/20 0.34
THRB P10828 1/20 0.34
LMNA P02545 1/20 0.34
CNR2 P34972 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL283999 0.78 ESR1 (0.47) NAAAKDM4EALDH1A1HPGDHSD17B10
SCHEMBL284665 0.78 ESR1 (0.47) NAAAKDM4EALDH1A1HPGDHSD17B10
SCHEMBL668699 0.78 ESR1 (0.47) NAAAKDM4EALDH1A1HPGDHSD17B10
SCHEMBL283748 0.78 ESR1 (0.47) NAAAKDM4EALDH1A1HPGDHSD17B10
SCHEMBL283820 0.78 ESR1 (0.47) NAAAKDM4EALDH1A1HPGDHSD17B10
SCHEMBL2947334 0.78 ESR1 (0.47) NAAAKDM4EALDH1A1HPGDHSD17B10
SCHEMBL283373 0.78 ESR1 (0.47) NAAAKDM4EALDH1A1HPGDHSD17B10
SCHEMBL284260 0.78 ESR1 (0.47) NAAAKDM4EALDH1A1HPGDHSD17B10
SCHEMBL284042 0.74 ESR1 (0.51) NAAAKDM4EALDH1A1HPGDHSD17B10
SCHEMBL283613 0.74 ESR1 (0.51) NAAAKDM4EALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021211982-A2 REGIOSELECTIVE SYNTHESIS OF SUBSTITUTED COMPOUNDS OREGON STATE UNIVERSITY (US) 2021-10-21 WO claimed
WO-2021211982-A2 REGIOSELECTIVE SYNTHESIS OF SUBSTITUTED COMPOUNDS OREGON STATE UNIVERSITY (US) 2021-10-21 WO disclosed