Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.41 |
| ▸ | PTGES | O14684 | 2/20 | 0.41 |
| ▸ | KCNB1 | Q14721 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22798235 | 0.88 | SCN9A (0.64) | SCN9ATRPV1PPARAPPARDMCHR1 | |
| SCHEMBL20595174 | 0.81 | SCN9A (0.51) | SCN9ATRPV1PPARAPPARDMCHR1 | |
| SCHEMBL22797817 | 0.80 | SCN9A (0.49) | SCN9ATRPV1PPARAPPARDMCHR1 | |
| SCHEMBL20596684 | 0.79 | SCN9A (0.63) | SCN9ATRPV1PPARAPPARDMCHR1 | |
| SCHEMBL22798424 | 0.77 | GSK3B (0.53) | SCN9A | |
| SCHEMBL22809549 | 0.75 | GSK3A (0.42) | SCN9ATRPV1PPARAPPARDMCHR1 | |
| SCHEMBL20595154 | 0.75 | SCN9A (0.76) | SCN9AMRGPRX4 | |
| SCHEMBL22797749 | 0.73 | SCN9A (0.60) | SCN9AMCHR1KCNB1 | |
| SCHEMBL30449857 | 0.73 | SCN9A (0.60) | SCN9AMCHR1KCNB1 | |
| SCHEMBL22798240 | 0.73 | SCN9A (0.51) | SCN9ATRPV1PPARAPPARDMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11154544-B2 | Amide derivatives as Nav1.7 and Nav1.8 blockers | RAQUALIA PHARMA INC. (JP) | 2021-10-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11154544-B2 | Amide derivatives as Nav1.7 and Nav1.8 blockers | SCN8A, SCN7A, SCN1A | SCN9A 9/4885TRPV1 57/4885PPARA 2273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.