Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 19/20 | 0.65 |
| ▸ | PDE4C | Q08493 | 17/20 | 0.65 |
| ▸ | PDE4A | P27815 | 11/20 | 0.65 |
| ▸ | PDE4D | Q08499 | 11/20 | 0.65 |
| ▸ | HTR2B | P41595 | 1/20 | 0.57 |
| ▸ | TNF | P01375 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28811594 | 1.00 | PDE4B (0.65) | PDE4BPDE4CPDE4APDE4DHTR2B | |
| SCHEMBL29860675 | 1.00 | PDE4B (0.65) | PDE4BPDE4CPDE4APDE4DHTR2B | |
| SCHEMBL23499804 | 0.90 | PDE4B (0.65) | PDE4BPDE4CPDE4APDE4DHTR2B | |
| SCHEMBL23499797 | 0.90 | PDE4B (0.65) | PDE4BPDE4CPDE4APDE4DHTR2B | |
| SCHEMBL31063328 | 0.90 | PDE4B (0.65) | PDE4BPDE4CPDE4APDE4DHTR2B | |
| SCHEMBL15198844 | 0.88 | PDE4B (0.78) | PDE4BPDE4CPDE4APDE4DHTR2B | |
| SCHEMBL29651471 | 0.88 | PDE4B (0.78) | PDE4BPDE4CPDE4APDE4DHTR2B | |
| SCHEMBL1193538 | 0.88 | PDE4B (0.78) | PDE4BPDE4CPDE4APDE4DHTR2B | |
| SCHEMBL21750008 | 0.88 | PDE4B (0.76) | PDE4BPDE4CPDE4APDE4DHTR2B | |
| SCHEMBL21750009 | 0.88 | PDE4B (0.76) | PDE4BPDE4CPDE4APDE4DHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110291065-B | Novel isoindoline derivative, pharmaceutical composition and application thereof | 康朴生物医药技术（上海）有限公司 | 2022-08-19 | — | — | CN | disclosed |
| EP-3590924-B1 | NOVEL ISOINDOLINE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | KANGPU BIOPHARMACEUTICALS LTD (CN) | 2021-10-27 | — | — | EP | disclosed |