Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 9/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | BCL2 | P10415 | 3/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | F13A1 | P00488 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | TGM1 | P22735 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22368503 | 1.00 | MEN1 (0.36) | MEN1KMT2AMCL1POLBALDH1A1 | |
| SCHEMBL19990607 | 0.92 | KMT2A (0.35) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL23927097 | 0.86 | MCL1 (0.35) | MEN1KMT2AMCL1POLBALDH1A1 | |
| SCHEMBL20009188 | 0.81 | KMT2A (0.37) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL19990660 | 0.80 | KMT2A (0.36) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL22368492 | 0.80 | KMT2A (0.36) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL19990663 | 0.79 | KMT2A (0.34) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL15347117 | 0.79 | MEN1 (0.43) | MEN1KMT2AMCL1ALDH1A1JAK2 | |
| SCHEMBL15347277 | 0.78 | MEN1 (0.42) | MEN1KMT2AMCL1ALDH1A1JAK2 | |
| SCHEMBL15347310 | 0.78 | MEN1 (0.42) | MEN1KMT2AMCL1ALDH1A1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3698796-B1 | PHARMACEUTICAL COMBINATION OF A TRICYCLIC BETA-LACTAMASE INHIBITOR WITH SPECIFIC BETA-LACTAM ANTIBIOTICS | NOVARTIS AG (CH) | 2021-10-27 | — | — | EP | disclosed |