Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 17/20 | 0.55 |
| ▸ | CDK2 | P24941 | 15/20 | 0.55 |
| ▸ | CDK7 | P50613 | 14/20 | 0.55 |
| ▸ | CCNE1 | P24864 | 13/20 | 0.55 |
| ▸ | CCNB1 | P14635 | 11/20 | 0.55 |
| ▸ | CCNH | P51946 | 11/20 | 0.55 |
| ▸ | CDK4 | P11802 | 10/20 | 0.55 |
| ▸ | CCND1 | P24385 | 10/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.55 |
| ▸ | CDK5 | Q00535 | 8/20 | 0.54 |
| ▸ | CDK9 | P50750 | 4/20 | 0.54 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.54 |
| ▸ | CLK2 | P49760 | 2/20 | 0.54 |
| ▸ | CSNK1G2 | P78368 | 2/20 | 0.54 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.54 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.54 |
| ▸ | CSNK1G1 | Q9HCP0 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19112165 | 0.86 | CDK1 (0.70) | CDK1CDK2CDK7CCNE1CCNB1 | |
| SCHEMBL19112159 | 0.86 | CDK1 (0.70) | CDK1CDK2CDK7CCNE1CCNB1 | |
| SCHEMBL34470227 | 0.86 | CDK1 (0.70) | CDK1CDK2CDK7CCNE1CCNB1 | |
| SCHEMBL30356164 | 0.86 | CDK1 (0.70) | CDK1CDK2CDK7CCNE1CCNB1 | |
| Hydrochloric Acid SCHEMBL30268952 | 0.85 | CDK1 (0.69) | CDK1CDK2CDK7CCNE1CCNB1 | |
| Hydrochloric Acid SCHEMBL23927314 | 0.85 | CDK1 (0.69) | CDK1CDK2CDK7CCNE1CCNB1 | |
| Hydrochloric Acid SCHEMBL23927312 | 0.85 | CDK1 (0.69) | CDK1CDK2CDK7CCNE1CCNB1 | |
| SCHEMBL23927311 | 0.84 | NPSR1 (0.54) | CDK1CDK2CDK7CCNE1CCNB1 | |
| SCHEMBL16322125 | 0.82 | KDM4E (0.79) | CDK1CDK2CDK7CCNE1CCNB1 | |
| SCHEMBL19112201 | 0.80 | CDK1 (0.67) | CDK1CDK2CDK7CCNE1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4139308-B1 | PURINE DERIVATIVES AS DRUGS FOR THE TREATMENT OF NEONATAL HYPOXIA-ISCHEMIA BRAIN INJURY AND RELATED DISEASES | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2024-07-17 | — | — | EP | disclosed |
| US-20230181592-A1 | PURINE DERIVATIVES AS DRUGS FOR THE TREATMENT OF NEONATAL HYPOXIA-ISCHEMIA BRAIN INJURY AND RELATED DISEASES | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2023-06-15 | — | — | US | disclosed |
| EP-4139308-A1 | PURINE DERIVATIVES AS DRUGS FOR THE TREATMENT OF NEONATAL HYPOXIA-ISCHEMIA BRAIN INJURY AND RELATED DISEASES | Commissariat à l'Energie Atomique et aux Energies Alternatives (FR) | 2023-03-01 | — | — | EP | disclosed |
| WO-2021214315-A1 | PURINE DERIVATIVES AS DRUGS FOR THE TREATMENT OF NEONATAL HYPOXIA-ISCHEMIA BRAIN INJURY AND RELATED DISEASES | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2021-10-28 | — | — | WO | disclosed |
| EP-3901154-A1 | PURINE DERIVATIVES AS DRUGS FOR THE TREATMENT OF NEONATAL HYPOXIA-ISCHEMIA BRAIN INJURY AND RELATED DISEASES | Commissariat à l'énergie atomique et aux énergies alternatives (FR) | 2021-10-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230181592-A1 | PURINE DERIVATIVES AS DRUGS FOR THE TREATMENT OF NEONATAL HYPOXIA-ISCHEMIA BRAIN INJURY AND RELATED DISEASES | ADORA1, OXGR1, ADORA2A | CDK1 981/4885CDK2 1842/4885CDK7 2096/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.