Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SAE1 | Q9UBE0 | 18/20 | 0.45 |
| ▸ | UBA2 | Q9UBT2 | 18/20 | 0.45 |
| ▸ | NAE1 | Q13564 | 15/20 | 0.45 |
| ▸ | UBA3 | Q8TBC4 | 15/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23927333 | 0.83 | SAE1 (0.63) | SAE1UBA2NAE1UBA3CA1 | |
| SCHEMBL23927334 | 0.83 | SAE1 (0.63) | SAE1UBA2NAE1UBA3CA1 | |
| SCHEMBL23927365 | 0.83 | SAE1 (0.63) | SAE1UBA2NAE1UBA3CA1 | |
| SCHEMBL17421675 | 0.73 | SAE1 (0.80) | SAE1UBA2NAE1UBA3CA1 | |
| SCHEMBL17398497 | 0.73 | SAE1 (0.80) | SAE1UBA2NAE1UBA3CA1 | |
| SCHEMBL23927335 | 0.73 | SAE1 (0.80) | SAE1UBA2NAE1UBA3CA1 | |
| SCHEMBL25395436 | 0.63 | SAE1 (0.71) | SAE1UBA2NAE1UBA3 | |
| SCHEMBL25395426 | 0.63 | SAE1 (0.71) | SAE1UBA2NAE1UBA3 | |
| SCHEMBL17410132 | 0.62 | SAE1 (1.00) | SAE1UBA2NAE1UBA3CA1 | |
| SCHEMBL17421655 | 0.62 | SAE1 (1.00) | SAE1UBA2NAE1UBA3CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3901159-A1 | HETEROARYL COMPOUNDS USEFUL AS INHIBITORS OF SUMO ACTIVATING ENZYME | Millennium Pharmaceuticals, Inc. (US) | 2021-10-27 | — | — | EP | disclosed |