Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.49 |
| ▸ | RARG | P13631 | 4/20 | 0.49 |
| ▸ | RARA | P10276 | 3/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19639510 | 0.86 | RARB (0.50) | RARBRARGRARAS1PR1MAPT | |
| SCHEMBL19639449 | 0.86 | RARB (0.67) | RARBRARGRARAMAPTNR1H4 | |
| SCHEMBL17847412 | 0.85 | RARB (0.51) | RARBRARGRARAS1PR1S1PR3 | |
| SCHEMBL17847377 | 0.84 | RARB (0.49) | RARBRARGRARAS1PR1S1PR3 | |
| SCHEMBL19639499 | 0.83 | RARB (0.51) | RARBRARGRARAS1PR1MAPT | |
| SCHEMBL19639416 | 0.83 | RARB (0.50) | RARBRARGRARAS1PR1S1PR3 | |
| SCHEMBL19639455 | 0.82 | RARB (0.49) | RARBRARGRARAS1PR1MAPT | |
| SCHEMBL17847385 | 0.81 | RARB (0.64) | RARBRARGRARAS1PR1MAPT | |
| SCHEMBL19639487 | 0.81 | RARB (0.48) | RARBRARGRARAS1PR1MAPT | |
| SCHEMBL23952923 | 0.77 | RARB (0.42) | RARBRARGRARAS1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233806-B1 | HETEROCYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND USE THEREOF IN MEDICINE AS WELL AS IN COSMETICS | GALDERMA RES & DEV (FR) | 2021-10-27 | — | — | EP | disclosed |