Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HRH4 | Q9H3N8 | 8/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12228287 | 0.72 | SMN1; SMN2 (1.00) | SMN1; SMN2HRH4HTR3AHRH3CHRM2 | |
| SCHEMBL22096056 | 0.72 | SMN1; SMN2 (1.00) | SMN1; SMN2HRH4HTR3AHRH3CHRM2 | |
| SCHEMBL4316806 | 0.72 | SMN1; SMN2 (1.00) | SMN1; SMN2HRH4HTR3AHRH3CHRM2 | |
| SCHEMBL4316809 | 0.72 | SMN1; SMN2 (1.00) | SMN1; SMN2HRH4HTR3AHRH3CHRM2 | |
| SCHEMBL26786348 | 0.68 | SMN1; SMN2 (0.67) | SMN1; SMN2HRH4HTR3AHRH3CHRM2 | |
| SCHEMBL13754187 | 0.67 | SMN1; SMN2 (0.33) | SMN1; SMN2 | |
| SCHEMBL22096057 | 0.66 | SMN1; SMN2 (0.61) | SMN1; SMN2HRH4HTR3AHRH3CHRM2 | |
| SCHEMBL18325628 | 0.63 | HRH4 (1.00) | HRH4HTR3AHRH3 | |
| SCHEMBL8711763 | 0.63 | HRH3 (0.56) | SMN1; SMN2HRH4HTR3AHRH3CHRM2 | |
| SCHEMBL23054324 | 0.61 | SMN1; SMN2 (0.57) | SMN1; SMN2HRH4HTR3AHRH3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12153055-B2 | Methods of detecting and treating airway inflammatory diseases | NATIONAL JEWISH HEALTH (US) | 2024-11-26 | — | — | US | disclosed |
| US-20210333289-A1 | METHODS OF DETECTING AND TREATING AIRWAY INFLAMMATORY DISEASES | NATIONAL JEWISH HEALTH | 2021-10-28 | — | — | US | disclosed |