SCHEMBL23928762

SCHEMBL23928762

O=c1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2OCCS)c(=O)[nH]1

nearest known ligand 0.69

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ SLC28A1 O00337 1/20 0.68
▸ SLC28A2 O43868 1/20 0.68
▸ SLC29A1 Q99808 1/20 0.68
▸ SLC28A3 Q9HAS3 1/20 0.68
▸ P2RY2 P41231 10/20 0.49
▸ P2RY6 Q15077 9/20 0.49
▸ P2RY14 Q15391 6/20 0.49
▸ P2RY4 P51582 5/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20942747 0.92 SLC28A1 (0.70) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL28804995 0.90 SLC28A1 (0.73) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL4453558 0.89 SLC28A1 (0.68) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL19726985 0.89 SLC28A1 (0.68) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL4453556 0.89 SLC28A1 (0.68) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL16243264 0.89 SLC28A1 (0.68) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL18720102 0.89 SLC28A1 (0.68) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL20815980 0.88 SLC28A1 (0.71) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL5420941 0.88 SLC28A1 (0.71) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL2299811 0.88 SLC28A1 (0.67) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115997016-A Composition comprising nucleic acid nanoparticles having modular functional groups 西克斯福德生物科学有限公司 2023-04-21 — — CN disclosed
EP-4143316-A2 COMPOSITIONS CONTAINING NUCLEIC ACID NANOPARTICLES WITH MODULAR FUNCTIONALITY Sixfold Bioscience Ltd. (GB) 2023-03-08 — — EP disclosed
US-11357865-B2 Compositions containing nucleic acid nanoparticles with modular functionality Sixfold Bioscience Ltd. (GB) 2022-06-14 — — US disclosed
WO-2021220053-A2 COMPOSITIONS CONTAINING NUCLEIC ACID NANOPARTICLES WITH MODULAR FUNCTIONALITY Sixfold Bioscience Ltd. (GB) 2021-11-04 — — WO disclosed
US-20210330810-A1 COMPOSITIONS CONTAINING NUCLEIC ACID NANOPARTICLES WITH MODULAR FUNCTIONALITY Sixfold Bioscience Ltd. (GB) 2021-10-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11357865-B2 Compositions containing nucleic acid nanoparticles with modular functionality NCL, NSUN3, POLN SLC28A1 3646/4885SLC28A2 3993/4885SLC29A1 840/4885
US-20210330810-A1 COMPOSITIONS CONTAINING NUCLEIC ACID NANOPARTICLES WITH MODULAR FUNCTIONALITY NCL, NSUN3, POLN SLC28A1 3646/4885SLC28A2 3993/4885SLC29A1 840/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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