Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.68 |
| ▸ | ADH1B | P00325 | 3/20 | 0.62 |
| ▸ | ADH1A | P07327 | 3/20 | 0.62 |
| ▸ | ADH7 | P40394 | 3/20 | 0.62 |
| ▸ | ADH1C | P00326 | 2/20 | 0.62 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.62 |
| ▸ | ADH4 | P08319 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | FAAH | O00519 | 2/20 | 0.60 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.60 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.50 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.50 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.50 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25954739 | 1.00 | TSHR (0.68) | TSHRADH1BADH1AADH7ADH1C | |
| SCHEMBL27789560 | 1.00 | TSHR (0.68) | TSHRADH1BADH1AADH7ADH1C | |
| SCHEMBL17779397 | 1.00 | TSHR (0.68) | TSHRADH1BADH1AADH7ADH1C | |
| SCHEMBL25200621 | 1.00 | TSHR (0.68) | TSHRADH1BADH1AADH7ADH1C | |
| SCHEMBL28736426 | 1.00 | TSHR (0.68) | TSHRADH1BADH1AADH7ADH1C | |
| SCHEMBL25274699 | 0.95 | TSHR (0.76) | TSHRADH1BADH1AADH7ADH1C | |
| SCHEMBL25093179 | 0.95 | TSHR (0.76) | TSHRADH1BADH1AADH7ADH1C | |
| SCHEMBL3022776 | 0.95 | TSHR (0.76) | TSHRADH1BADH1AADH7ADH1C | |
| SCHEMBL25093248 | 0.95 | TSHR (0.76) | TSHRADH1BADH1AADH7ADH1C | |
| SCHEMBL3031672 | 0.93 | TSHR (0.71) | TSHRADH1BADH1AADH7ADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4168009-A1 | CONJUGATES OF A CELL-BINDING MOLECULE WITH CAMPTOTHECIN ANALOGS | Hangzhou DAC Biotech Co., Ltd. (CN) | 2023-04-26 | — | — | EP | disclosed |
| WO-2022078524-A4 | SPECIFIC CONJUGATION OF AN ANTIBODY | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2022-12-08 | — | — | WO | disclosed |
| WO-2022078524-A2 | SPECIFIC CONJUGATION OF AN ANTIBODY | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2022-04-21 | — | — | WO | disclosed |
| WO-2021212638-A1 | CONJUGATES OF A CELL-BINDING MOLECULE WITH CAMPTOTHECIN ANALOGS | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2021-10-28 | — | — | WO | disclosed |