Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 11/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD5 | P21918 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21745145 | 0.88 | EGLN1 (0.39) | EGLN1RETTDO2 | |
| Ammonia Solution, Strong SCHEMBL22041901 | 0.86 | EGLN1 (0.39) | EGLN1RETTDO2 | |
| Hydrochloric Acid SCHEMBL28716738 | 0.85 | EGLN1 (0.38) | EGLN1RETTDO2 | |
| SCHEMBL23957701 | 0.84 | RET (0.40) | EGLN1RET | |
| SCHEMBL22041856 | 0.81 | EGLN1 (0.40) | RAB9APKMEGLN1RETTDO2 | |
| SCHEMBL23929886 | 0.81 | EGLN1 (0.39) | EGLN1RETTDO2 | |
| SCHEMBL22041784 | 0.81 | EGLN1 (0.42) | EGLN1RET | |
| SCHEMBL29631497 | 0.81 | EGLN1 (0.42) | EGLN1RET | |
| SCHEMBL23930252 | 0.81 | RET (0.41) | EGLN1RETTDO2 | |
| SCHEMBL30175308 | 0.81 | RET (0.41) | EGLN1RETTDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021213476-A1 | PYRAZOLO[1,5-A]PYRIDINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND COMPOSITION AND USE THEREOF | 深圳晶泰科技有限公司 (CN) | 2021-10-28 | — | — | WO | disclosed |