Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 18/20 | 0.85 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | BLM | P54132 | 2/20 | 0.59 |
| ▸ | RECQL | P46063 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | GLA | P06280 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | STAT6 | P42226 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Namitecan SCHEMBL29551605 | 1.00 | TOP1 (0.85) | TOP1KDM4ERAB9ABLMRECQL | |
| Namitecan SCHEMBL24685130 | 1.00 | TOP1 (0.85) | TOP1KDM4ERAB9ABLMRECQL | |
| Namitecan SCHEMBL5065702 | 1.00 | TOP1 (0.85) | TOP1KDM4ERAB9ABLMRECQL | |
| Namitecan SCHEMBL29482428 | 1.00 | TOP1 (0.85) | TOP1KDM4ERAB9ABLMRECQL | |
| SCHEMBL5065698 | 0.96 | TOP1 (0.88) | TOP1KDM4ERAB9ABLMRECQL | |
| SCHEMBL13944309 | 0.94 | TOP1 (0.88) | TOP1KDM4ERAB9ABLMRECQL | |
| SCHEMBL3914332 | 0.93 | TOP1 (0.90) | TOP1KDM4ERAB9ABLMRECQL | |
| SCHEMBL25130176 | 0.93 | TOP1 (0.85) | TOP1KDM4ERAB9ABLMRECQL | |
| SCHEMBL2028388 | 0.93 | TOP1 (0.85) | TOP1KDM4ERAB9ABLMRECQL | |
| SCHEMBL3189465 | 0.92 | TOP1 (0.97) | TOP1KDM4ERAB9ABLMRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250319079-A1 | COMPOSITION CONTAINING ANTITUMOR DRUG, AND PREPARATION METHOD THEREOF AND USE THEREOF | KUNSHAN XINYUNDA BIOTECH CO., LTD. (CN) | 2025-10-16 | — | — | US | disclosed |
| US-12370187-B2 | Composition containing antitumor drug, and preparation method thereof and use thereof | KUNSHAN XINYUNDA BIOTECH CO., LTD. (CN) | 2025-07-29 | — | — | US | disclosed |
| EP-4417204-A1 | COMPOSITION CONTAINING ANTITUMOR DRUG, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Kunshan Xinyunda Biotech Co., Ltd. (CN) | 2024-08-21 | — | — | EP | disclosed |
| US-20240252482-A1 | COMPOSITION CONTAINING ANTITUMOR DRUG, AND PREPARATION METHOD THEREOF AND USE THEREOF | KUNSHAN XINYUNDA BIOTECH CO., LTD. (CN) | 2024-08-01 | — | — | US | disclosed |
| CN-117547535-A | Composition containing antitumor drug and preparation method and application thereof | 昆山新蕴达生物科技有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-117098536-A | Composition containing antitumor drug and preparation method and application thereof | 昆山新蕴达生物科技有限公司 | 2023-11-21 | — | — | CN | disclosed |
| WO-2023061393-A1 | COMPOSITION CONTAINING ANTITUMOR DRUG, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 昆山新蕴达生物科技有限公司 | 2023-04-20 | — | — | WO | disclosed |
| WO-2021213327-A1 | COMPOSITION CONTAINING 7-ETHYL-10-HYDROXYCAMPTOTHECIN, PREPARATION METHOD THEREFOR AND USE THEREOF | 昆山新蕴达生物科技有限公司 (CN) | 2021-10-28 | — | — | WO | disclosed |
| CN-113423388-A | Method for preparing nanocrystals with improved bioavailability and formulation of such nanocrystal formulations for anticancer therapy | 托马斯拔佳大学 | 2021-09-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240252482-A1 | COMPOSITION CONTAINING ANTITUMOR DRUG, AND PREPARATION METHOD THEREOF AND USE THEREOF | MTTP, CETP, ALB | TOP1 72/4885KDM4E 3238/4885RAB9A 2621/4885 |
| US-12370187-B2 | Composition containing antitumor drug, and preparation method thereof and use thereof | MTTP, CETP, ALB | TOP1 72/4885KDM4E 3238/4885RAB9A 2621/4885 |
| US-20250319079-A1 | COMPOSITION CONTAINING ANTITUMOR DRUG, AND PREPARATION METHOD THEREOF AND USE THEREOF | MTTP, CETP, ALB | TOP1 72/4885KDM4E 3238/4885RAB9A 2621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.