Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 20/20 | 0.36 |
| ▸ | VHL | P40337 | 1/20 | 0.35 |
| ▸ | CDK7 | P50613 | 1/20 | 0.35 |
| ▸ | CCNH | P51946 | 1/20 | 0.35 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23931957 | 1.00 | KRAS (0.36) | KRASVHLCDK7CCNHMNAT1 | |
| SCHEMBL29622577 | 0.85 | IDH1 (0.41) | KRASVHLCDK7CCNHMNAT1 | |
| SCHEMBL19947718 | 0.83 | KRAS (0.36) | KRASVHLCDK7CCNHMNAT1 | |
| SCHEMBL19947719 | 0.83 | KRAS (0.36) | KRASVHLCDK7CCNHMNAT1 | |
| SCHEMBL23827678 | 0.82 | KRAS (0.35) | KRASVHLCDK7CCNHMNAT1 | |
| SCHEMBL23827680 | 0.82 | KRAS (0.35) | KRASVHLCDK7CCNHMNAT1 | |
| SCHEMBL22692014 | 0.80 | KRAS (0.35) | KRASVHLCDK7CCNHMNAT1 | |
| SCHEMBL22692013 | 0.80 | KRAS (0.35) | KRASVHLCDK7CCNHMNAT1 | |
| SCHEMBL19948645 | 0.79 | KRAS (0.42) | KRASVHLCDK7CCNHMNAT1 | |
| SCHEMBL19617546 | 0.79 | KRAS (0.42) | KRASVHLCDK7CCNHMNAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022087624-A1 | COMPOUNDS AS RAS INHIBITORS AND USES THEREOF | BIOARDIS LLC (US) | 2022-04-28 | — | — | WO | disclosed |
| WO-2021216770-A1 | SUBSTITUTED TETRAHYDROQUINAZOLINE COMPOUNDS AS KRAS INHIBITORS | ACCUTAR BIOTECHNOLOGY INC. (US) | 2021-10-28 | — | — | WO | disclosed |