Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.51 |
| ▸ | PRF1 | P14222 | 1/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.49 |
| ▸ | GSK3B | P49841 | 2/20 | 0.49 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.49 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 1/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | GRM5 | P41594 | 4/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.45 |
| ▸ | PARP11 | Q9NR21 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14683952 | 0.88 | NPC1 (0.58) | SMYD3PRF1CLK4GSK3BDAPK3 | |
| SCHEMBL14639939 | 0.86 | SMYD3 (0.49) | SMYD3PRF1CLK4GSK3BDAPK3 | |
| SCHEMBL14332678 | 0.82 | SMYD3 (0.58) | SMYD3PRF1CLK4GSK3BDAPK3 | |
| SCHEMBL19691136 | 0.81 | PRF1 (0.66) | SMYD3PRF1CLK4GSK3BDAPK3 | |
| SCHEMBL29544439 | 0.81 | PRF1 (0.66) | SMYD3PRF1CLK4GSK3BDAPK3 | |
| SCHEMBL24812335 | 0.80 | SMYD3 (0.50) | SMYD3PRF1CLK4GSK3BDAPK3 | |
| SCHEMBL25139737 | 0.80 | SMYD3 (0.50) | SMYD3PRF1CLK4GSK3BDAPK3 | |
| SCHEMBL4611577 | 0.80 | SMYD3 (0.53) | SMYD3PRF1CLK4GSK3BDAPK3 | |
| SCHEMBL15759502 | 0.80 | SMYD3 (0.60) | SMYD3PRF1CLK4GSK3BDAPK3 | |
| SCHEMBL31098601 | 0.80 | SMYD3 (0.53) | SMYD3PRF1CLK4GSK3BDAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021217040-A1 | CARBAMATE AND UREA DERIVATIVES | IMMVENTION THERAPEUTIX (US) | 2021-10-28 | — | — | WO | claimed |