Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 3/20 | 0.45 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4742061 | 0.76 | GAA (0.56) | GAAMAPTSLC18A3SIGMAR1PIM1 | |
| SCHEMBL31490454 | 0.76 | GAA (0.56) | GAAMAPTSLC18A3SIGMAR1PIM1 | |
| SCHEMBL9253267 | 0.75 | SLC18A3 (0.52) | GAASLC18A3SIGMAR1MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL8090454 | 0.74 | GAA (0.54) | GAAMAPTSLC18A3SIGMAR1PIM1 | |
| SCHEMBL6874305 | 0.74 | MAPT (0.54) | GAAMAPTMAP1LC3BBRD4SLC18A3 | |
| SCHEMBL449180 | 0.74 | MAPT (0.82) | GAAMAPTMAP1LC3BBRD4SLC18A3 | |
| SCHEMBL23229609 | 0.72 | GAA (0.42) | GAAMAPTMAP1LC3BBRD4SLC18A3 | |
| SCHEMBL9746732 | 0.72 | SMN1; SMN2 (0.56) | GAAMAPTMAP1LC3BSMN1; SMN2TDP1 | |
| SCHEMBL17070910 | 0.72 | MAPT (0.57) | GAAMAPTMAP1LC3BBRD4SMN1; SMN2 | |
| SCHEMBL41763 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021217040-A1 | CARBAMATE AND UREA DERIVATIVES | IMMVENTION THERAPEUTIX (US) | 2021-10-28 | — | — | WO | claimed |