Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23933236 | 1.00 | TSHR (0.43) | TSHRNPSR1EPHX2ALDH1A1 | |
| SCHEMBL23933276 | 1.00 | TSHR (0.43) | TSHRNPSR1EPHX2ALDH1A1 | |
| SCHEMBL2343747 | 0.82 | EPHX2 (0.36) | NPSR1EPHX2ALDH1A1 | |
| SCHEMBL4806381 | 0.81 | TSHR (0.42) | TSHRNPSR1EPHX2 | |
| SCHEMBL13005842 | 0.80 | NPSR1 (0.49) | TSHRNPSR1EPHX2ALDH1A1 | |
| SCHEMBL4340777 | 0.77 | NPSR1 (0.47) | TSHRNPSR1EPHX2ALDH1A1 | |
| SCHEMBL1397825 | 0.77 | NPSR1 (0.47) | TSHRNPSR1EPHX2ALDH1A1 | |
| SCHEMBL1156342 | 0.77 | TSHR (0.43) | TSHRNPSR1EPHX2 | |
| SCHEMBL23933250 | 0.76 | NPSR1 (0.46) | TSHRNPSR1EPHX2ALDH1A1 | |
| SCHEMBL23933249 | 0.76 | NPSR1 (0.46) | TSHRNPSR1EPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021217040-A1 | CARBAMATE AND UREA DERIVATIVES | IMMVENTION THERAPEUTIX (US) | 2021-10-28 | — | — | WO | disclosed |