Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 17/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18825206 | 1.00 | DHODH (1.00) | DHODHKMT2AGAASMN1; SMN2MEN1 | |
| SCHEMBL29471117 | 1.00 | DHODH (1.00) | DHODHKMT2AGAASMN1; SMN2MEN1 | |
| SCHEMBL18825207 | 0.91 | DHODH (1.00) | DHODHKMT2AGAASMN1; SMN2 | |
| SCHEMBL23934837 | 0.91 | DHODH (1.00) | DHODHKMT2AGAASMN1; SMN2 | |
| SCHEMBL18825236 | 0.89 | DHODH (1.00) | DHODHKMT2AGAASMN1; SMN2 | |
| SCHEMBL18825211 | 0.89 | DHODH (1.00) | DHODHKMT2AGAASMN1; SMN2MEN1 | |
| SCHEMBL18825232 | 0.89 | DHODH (1.00) | DHODHKMT2AGAASMN1; SMN2 | |
| SCHEMBL18825169 | 0.89 | DHODH (1.00) | DHODHKMT2AGAASMN1; SMN2MEN1 | |
| SCHEMBL18825168 | 0.89 | DHODH (1.00) | DHODHKMT2AGAASMN1; SMN2MEN1 | |
| SCHEMBL18825164 | 0.89 | DHODH (1.00) | DHODHKMT2AGAASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3974424-A1 | TETRAHYDROINDAZOLES AND MEDICAL USES THEREOF | Genase Therapeutics B.V. (NL) | 2022-03-30 | — | — | EP | disclosed |
| EP-3371172-B1 | TETRAHYDROINDAZOLES AND MEDICAL USES THEREOF | GENASE THERAPEUTICS B V (NL) | 2021-10-20 | — | — | EP | disclosed |